Biomedical research

Selected papers

Splichal I., Splichalova A., 2018. Experimental enteric bacterial infections in the pig. J. Infect. Dis, doi: 10.1093/infdis/jiy185.  

Splichalova A., Slavikova V., Splichalova Z., Splichal I., 2018. Preterm life in sterile conditions:  A study on germ-free, preterm piglets. Front. Immunol.,

Splichalova A., Splichal I., Rada V., Sonnenborn U., 2014. A modified MacConkey agar for selective enumeration of necrotoxigenic E. coli O55 and probiotic E. coli Nissle 1917. J. Microbiol. Methods 104, 82-86.

Splichalova A., Splichal I., 2012. Local and systemic occurrences of HMGB1 in gnotobiotic piglets infected with E. coli O55 are related to bacterial translocation and inflammatory cytokines. Cytokine 60, 597-600.

Rockova S., Rada V., Marsik P., Vlkova E., Bunesova V., Sklenar J., Splichal I., 2011. Growth of bifidobacteria and clostridia on human and cow milk saccharides. Anaerobe. 17, 223-225.

Splichalova A., Splichal I., Chmelarova P., Trebichavsky I., 2011. Alarmin HMGB1 is released in the small intestine of gnotobiotic piglets infected with enteric pathogens and its level in plasma reflects severity of sepsis. J Clin. Immunol. 31, 488-497.

Splichalova A., Trebichavsky I., Rada V., Vlkova E., Sonnenborn U., Splichal I., 2011. Interference of Bifidobacterium choerinum or Escherichia coli Nissle 1917 with Salmonella Typhimurium in gnotobiotic piglets correlates with cytokine patterns in blood and intestine. Clin. Exp. Immunol. 163, 242-249.

Trebichavsky I., Splichal I., Rada V., Splichalova A., 2010. Modulation of natural immunity in the gut by Escherichia coli strain Nissle 1917. Nutr. Rev. 68, 459-464.

Rada V., Splichal I., Rockova S., Grmanova M., Vlkova E., 2010. Susceptibility of bifidobacteria to lysozyme as a possible selection criterion for probiotic bifidobacterial strains. Biotechnol. Lett. 32, 451-455.

Trebichavsky I., Rada V., Splichalova A., Splichal I., 2009. Cross-talk of human gut with bifidobacteria. Nutr. Rev. 67, 77-82.

Splichal I., Splichalova A., Trebichavsky I., 2008. Cytokine response to Escherichia coli in gnotobiotic pigs. Folia Microbiol. (Praha) 53, 161-164.

Splichal I., Rychlik I., Gregorova D., Sebkova A., Trebichavsky I., Splichalova A., Muneta Y., Mori Y., 2007. Susceptibility of germ-free pigs to challenge with protease mutants of Salmonella enterica serovar Typhimurium. Immunobiology 212, 577-582.


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